Novel calpain and dna encoding the same

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/64 (2006.01) C07K 16/40 (2006.01) C12N 1/21 (2006.01) C12N 15/57 (2006.01) C12P 21/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2321270

A novel calpain protein which is specific for the retina in the eye tissue containing a protein having an amino acid sequence represented by SEQ ID NO:1 in Sequence Listing; a DNA represented by SEQ ID NO:2 in Sequence Listing which encodes the above protein; a vector containing this DNA; a transformant transformed by this vector; and a process for producing the calpain protein which comprises culturing the transformant.

On décrit une nouvelle protéine calpaine spécifique pour la rétine dans le tissu oculaire, qui contient une protéine ayant une séquence d'acide aminé correspondant au numéro d'identification de la séquence 1 dans la liste des séquences; un ADN correspondant au numéro d'identification de la séquence 2 dans la liste des séquences et codant ladite protéine; un vecteur contenant ledit ADN; un transformant transformé par ledit vecteur; et un procédé de production de la protéine calpaine consistant à cultiver ledit transformant.

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