Novel k99-5278 substance and a process for production thereof

Details Novel k99-5278 substance and a process for production thereof Novel k99-5278 substance and a process for production thereof

C - Chemistry, Metallurgy

12

P

C12P 17/08 (2006.01) A61K 31/365 (2006.01) A61P 31/04 (2006.01) A61P 31/10 (2006.01) C07D 313/00 (2006.01) C07D 315/00 (2006.01)

Patent

CA 2463722

Microorganisms belonging to the genus Streptomyces and being capable of producing K99-5278A, K99-5278B and K99-5278C, which are drugs efficacious against infection with so-called fungi such as molds and yeasts, are cultured in a medium to accumulate the K99-5278A, K99-5278B and K99-5278C in the culture medium. Then the K99-5278A, K99-5278B and K99-5278C are collected from the culture medium. The thus obtained substances are expected as being useful as novel antifungal agents.

L'invention concerne des micro-organismes appartenant au genreStreptomyces et pouvant produire K99-5278A, K99-5278B et K99-5278C, des médicaments efficaces contre l'infection par des champignons tels que moisissures et levures. Ces micro-organismes sont cultivés dans un milieu de culture dans lequel s'accumulent K99-5278A, K99-5278B et K99-5278C. Les matières K99-5278A, K99-5278B et K99-5278C sont ensuite extraites du milieu de culture. Les matières obtenues sont susceptibles d'être utiles comme nouveaux agents antifongiques.

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