Aqueous protein solutions stable to denaturation

Details Aqueous protein solutions stable to denaturation Aqueous protein solutions stable to denaturation

C - Chemistry, Metallurgy

07

K

167/103, 167/103

C07K 14/62 (2006.01) A61K 47/10 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1146069

HOE 79/F 103 K AQUEOUS PROTEIN SOLUTIONS STABLE TO DENATURATION Abstract of the disclosure: To prevent the denaturation of proteins in aqueous pro- tein solutions at interfaces a surface-active substance with chain-like basic structure the members of which have weakly hydrophobic and weakly hydrophilic zones in alternating ar- rangement is added to the said solution. The invention also relates to the treatment of surfaces with the said surface- active substances and to the handling and purification of proteins. The preferred protein is insulin.

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