Particle-forming compositions containing fused...

A - Human Necessities – 61 – K

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A61K 31/553 (2006.01) A61P 25/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2338546

A non-aqueous, particle-forming, fused pyrrolocarbazole-containing composition is disclosed. Upon contact with an aqueous medium, the particle-forming composition spontaneously disperses into suspended particles, thereby forming a stable suspension that provides greatly improved bioavailability of orally administered fused pyrrolocarbazole compounds.

L'invention concerne une composition contenant des pyrrolocarbazoles fusionnés, formant des particules, non aqueuse. Lors du contact avec un milieu aqueux, la composition formant des particules se disperse spontanément en particules suspendues, ce qui forme une suspension stable qui fournit une biodisponibilité grandement améliorée des composés de pyrrolocarbazoles fusionnés administrés oralement.

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