Aminoalkylphosphonates and related compounds as edg receptor...

Details Aminoalkylphosphonates and related compounds as edg receptor... Aminoalkylphosphonates and related compounds as edg receptor...

C - Chemistry, Metallurgy

07

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C07F 9/40 (2006.01) A61K 31/41 (2006.01) A61K 31/4192 (2006.01) A61K 31/4196 (2006.01) A61K 31/662 (2006.01) A61P 37/00 (2006.01) C07C 229/34 (2006.01) C07C 309/24 (2006.01) C07C 311/51 (2006.01) C07D 233/84 (2006.01) C07D 249/04 (2006.01) C07D 249/10 (2006.01) C07D 249/12 (2006.01) C07D 257/04 (2006.01) C07D 257/06 (2006.01) C07F 9/09 (2006.01) C07F 9/38 (2006.01)

Patent

CA 2477449

The present invention encompasses compounds of formula (II); as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.

L'invention concerne des composés de formule générale (II) ainsi que des sels et des hydrates pharmaceutiquement acceptables de ceux-ci. Ces composés servent à traiter des maladies et des états d'origine immunologique, de type rejet de greffe de moelle osseuse, d'organes et de tissus. L'invention concerne également des compositions pharmaceutiques et des procédés d'utilisation associés.

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