Substituted indazolyl sulfonamide and 2,3-dihydro-indolyl...

C - Chemistry – Metallurgy – 07 – D

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C07D 231/56 (2006.01) A61K 31/416 (2006.01) A61K 31/429 (2006.01) A61K 31/454 (2006.01) A61P 3/00 (2006.01) A61P 25/00 (2006.01) C07D 401/04 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2592858

The present invention relates to substituted indazolyl sulfonamide and 2,3- dihydro~indolyl sulfonamide compounds of general formula I, a process for their preparation, medicaments comprising said substituted indazolyl sulfonamide and 2,3-dihydro-indolyl sulfonamide compounds as well as the use of said substituted indazolyl sulfonamide and 2,3-dihydro-indolyl sulfonamide compounds for the preparation of medicaments, which are particularly suitable for the prophylaxis and/or treatment of disorders or diseases that are at least partially mediated via 5-HT6 receptors.

La présente invention se rapporte à des composés substitués d'indazolyle sulfonamide et de 2,3-dihydro-indolyle sulfonamide représentés par la formule générale (I), à un procédé de préparation de ces composés, à des médicaments comportant ces composés substitués d'indazolyle sulfonamide et de 2,3-dihydro-indolyle sulfonamide ainsi qu'à l'utilisation de ces composés substitués d'indazolyle sulfonamide et de 2,3-dihydro-indolyle sulfonamide pour la préparation de médicaments, ces composés s'avérant particulièrement adaptés à la prophylaxie et/ou au traitement de troubles ou de maladies qui sont au moins partiellement générés indirectement par les récepteurs 5-HT6.

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