Use of notch pathway interfering agents for treatment of...

Details Use of notch pathway interfering agents for treatment of... Use of notch pathway interfering agents for treatment of...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2546017

The present invention provides a method for reducing the severity of, or treatment of, plasma cell disorders. The method comprises the step of administering to an individual afflicted with a plasma cell disorder, a composition comprising an antibody directed to the extracellular portion of NOTCH or to JAG2.

L'invention concerne un procédé permettant de réduire la sévérité, ou le traitement des troubles plasmocytaires : administration à une personne souffrant de tels troubles d'une composition qui renferme un anticorps 5 orienté vers la partie extra-cellulaire du NOTCH ou vers JAG2.

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