Non-natural amino acids

Details Non-natural amino acids Non-natural amino acids

C - Chemistry, Metallurgy

07

C

C07C 229/00 (2006.01) C07C 57/30 (2006.01) C07C 205/00 (2006.01) C07D 231/06 (2006.01)

Patent

CA 2573109

This invention relates to non-natural desamino alkyl amino acid compounds, methods of making, and peptides containing these compounds as their N-terminus moieties. A preferred example is neurotensin (8-13) in which the N terminus is an alpha desamino, alpha methyl N,N dimethyl homolysine residue.

L'invention concerne des composés d'acides aminés d'alkyle non naturels, des procédés de fabrication et des peptides contenant ces composés en tant que leurs groupes fonctionnels N-terminaux. Un exemple préféré est la neurotensine (8-13) dans laquelle la terminaison N est un alpha désamino, résidu d'alpha méthyle N,N diméthyl homolysine.

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