Aptamers to von willebrand factor and their use as...

Details Aptamers to von willebrand factor and their use as... Aptamers to von willebrand factor and their use as...

A - Human Necessities

61

K

A61K 48/00 (2006.01)

Patent

CA 2579374

The invention relates generally to the field of nucleic acids and more particularly to aptamers capable of binding to von Willebrand Factor useful as therapeutics in and diagnositcs of thrombotic diseases and/or other diseases or disorders in which von Willebrand Factor mediated platelet aggregation has been implicated. The invention further relates to materials and methods for the administration of aptamers capable of binding to von Willebrand Factor.

D'une manière générale, la présente invention a trait au domaine des acides nucléiques et plus particulièrement aux aptamères capables de liaison au facteur de von Willebrand utiles en tant qu'agents thérapeutiques et diagnostiques de maladies thrombotiques et/ou d'autres maladies ou troubles dans lesquels est impliquée l'agrégation plaquettaire médiée par le facteur de von Willebrand. L'invention a également trait à des substances et des procédés pour l'administration d'aptamères capables de liaison au facteur de von Willebrand.

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