Multiple antigen glycopeptide carbohydrate, vaccine...

Details Multiple antigen glycopeptide carbohydrate, vaccine... Multiple antigen glycopeptide carbohydrate, vaccine...

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01) A61K 39/00 (2006.01) A61K 47/48 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) C07K 9/00 (2006.01) C07K 14/00 (2006.01) C07K 14/22 (2006.01) C07K 14/285 (2006.01) C07K 14/31 (2006.01) C07K 14/315 (2006.01) C07K 16/00 (2006.01) C07K 16/12 (2006.01) C12P 21/00 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2285018

A carbohydrate peptide conjugate comprising: a carrier comprising a dendrimeric poly-Lysine enabling multiple epitopes to be covalently attached thereto, at least one peptide comprising one T epitope or several identical or different T epitopes, at least one carbohydrate moiety, or a derivative thereof, containing B epitope, provided it is not a sialoside, or several identical or different epitopes. Use of this conjugate for inducing immune response.

Conjugué glucidique et peptidique composé d'un support comprenant une poly-lysine dendrimère permettant à des déterminants antigéniques multiples de lui être reliés de façon covalente; au moins un peptide comprenant un déterminant antigénique T ou plusieurs déterminants antigéniques T identiques ou différents; au moins une fraction glucide, ou un de ses dérivés, contenant un déterminant antigénique B, à condition que ce ne soit pas un sialoside, ou plusieurs déterminants antigéniques identiques ou différents. Utilisation de ce conjugué afin de déclencher une réaction immune.

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