Synergistic effects of nuclear transcription factor...

Details Synergistic effects of nuclear transcription factor... Synergistic effects of nuclear transcription factor...

A - Human Necessities

61

K

A61K 31/12 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2483340

The present invention provides methods of inhibiting metastasis of a tumor and methods of treating a tumor using a combination of an inhibitor of the activation of nuclear factor NF-.kappa.B and a cancer chemotherapeutic agent. In one embodiment of the present invention, combination of curcumin and paclitaxel (taxol) can be used to treat and inhibit metastasis of breast tumor.

la présente invention concerne des méthodes propres à inhiber les métastases d'une tumeur et à traiter une tumeur à l'aide d'une combinaison d'un inhibiteur du facteur d'activation du facteur nucléaire NF-?B et d'un agent chimiothérapeutique du cancer. Dans un mode de réalisation de la présente invention, on peut utiliser une combinaison de curcumine et de paclitaxel (taxol) pour traiter et inhiber les métastases de la tumeur du sein.

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