Mistletoe lectins as mucosal adjuvants

A - Human Necessities – 61 – K

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Details

A61K 39/39 (2006.01) A61P 31/00 (2006.01) A61P 31/22 (2006.01)

Patent

CA 2389080

The invention provides a method of increasing an immune response in a mammal. The method involves administering to the mammal an admixture comprising an immunogen and a plant lectin. The plant lectin acts as an adjuvant to increase an immune response against the immunogen. The method is especially well-suited for mucosal administration to humans and others mammals.

L'invention concerne une méthode d'augmentation d'une réponse immunitaire chez un mammifère. Cette méthode consiste à administrer à un mammifère un adjuvant contenant un immunogène et une lectine végétale. La lectine végétale agit comme un adjuvant pour accroître une réponse immunitaire contre l'immunogène. Cette méthode est notamment très appropriée à l'administration des muqueuses chez l'homme et les autres mammifères.

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