Sustained release compositions, methods for producing the...

A - Human Necessities – 61 – K

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A61K 9/52 (2006.01) A61K 9/16 (2006.01) A61K 38/09 (2006.01) A61K 47/12 (2006.01) A61K 47/34 (2006.01) A61P 5/24 (2006.01) A61P 13/08 (2006.01) A61P 15/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2378714

Sustained release compositions containing a physiologically active substance or its salt, hydroxynaphthoic acid or its salt and a lactic acid-glycolic acid polymer or its salt, wherein the product of the weight-average molecular weight of the lactic acid-glycolic acid polymer by the amount (µmol) of the terminal carboxyl group per unit mass (g) of the lactic acid-glycolic acid polymer is from 1,200,000 to 3,000,000 (inclusive); and drugs, etc. containing these sustained release compositions.

Cette invention a trait à des compositions à libération lente contenant une substance active du point de vue physiologique ou son sel, un acide hydroxynaphtoïque ou son sel et un polymère d'acide lactique acide glycolique. Le produit du poids moléculaire moyen en poids du polymère d'acide lactique acide glycolique par le volume (µmol) du groupe carboxyle terminal par masse unitaire (g) du polymère d'acide lactique acide glycolique est compris entre 1 200 000 à 3 000 000 (inclusivement). L'invention concerne également, entre autres, des médicaments contenant ces compositions à libération lente.

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