Coated drug delivery formulations

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/127 (2006.01) A61K 9/14 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01)

Patent

CA 2589736

The invention relates generally to methods of making formulations for delivering biological agents to a patient. In one aspect, proliposomal drug- delivery systems for medicaments are provided. In another aspect, coated proliposomal formulations for poorly water soluble drugs, and methods for making the same, are provided. Certain embodiments of the present invention provide enhanced stability and bioavailability for pharmaceutical formulations.

L'invention concerne, de manière générale, des procédés de préparation de formulations d'administration d'agents biologiques à un patient. Un premier aspect de l'invention se rapporte à des systèmes d'administration de médicaments proliposomiques pour médicaments. Un autre aspect se rapporte à des formulations proliposomiques enrobées pour médicaments faiblement hydrosolubles, ainsi qu'à des procédés de préparation de celles-ci. Certains modes de réalisation de l'invention présentent une stabilité et une biodisponibilité améliorées des formulations pharmaceutiques.

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