Metalloproteinase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 233/78 (2006.01) A61K 31/4166 (2006.01) A61K 31/4439 (2006.01) A61K 31/454 (2006.01) A61P 11/00 (2006.01) A61P 19/00 (2006.01) A61P 35/00 (2006.01) C07D 223/16 (2006.01) C07D 233/76 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/06 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2440473

Compounds of the formula (II) are useful as metalloproteinase inhibitors, especially as inhibitors of MMP12: (see formula ll)

L'invention se rapporte à des composés représentés par la formule (I) dans laquelle Z et SO¿2? (N6) ou N(R7)SO¿2? ou N(R7)SO¿2?N(R6), qui s'avèrent utiles en tant qu'inhibiteurs des métalloprotéinases, notamment en tant qu'inhibiteurs de MMP12.

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