Inactivated mycoplasma hyopneumoniae and uses therefor

Details Inactivated mycoplasma hyopneumoniae and uses therefor Inactivated mycoplasma hyopneumoniae and uses therefor

C - Chemistry, Metallurgy

12

N

C12N 1/36 (2006.01) A01K 67/027 (2006.01) A61K 39/02 (2006.01) A61K 39/10 (2006.01) A61K 39/102 (2006.01) A61K 39/116 (2006.01) A61K 39/39 (2006.01) C07K 14/30 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2129982

2129982 9316726 PCTABS00025 The invention relates to a method for making an inactivated vaccine of Mycoplasma hyopneumoniae by inactivating the bacteria with Thimerosal. The resulting bacterin is mixed with an adjuvant of aluminum hydroxide and DEAE dextran and injected into pigs. The resulting bacterin and adjuvant mixture can also be mixed with other bacteria such as Bordetella and Pasteurella, for further adjuvant effect. Protective immunity against mycoplasmal pneumonia is elicited in swine using these vaccines.

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