Substituted 1-amino-4-phenyl-dihydroisoquinolines, method...

Details Substituted 1-amino-4-phenyl-dihydroisoquinolines, method... Substituted 1-amino-4-phenyl-dihydroisoquinolines, method...

C - Chemistry, Metallurgy

07

D

C07D 217/22 (2006.01) A61K 31/472 (2006.01) A61K 31/4725 (2006.01) A61P 11/00 (2006.01) C07D 401/10 (2006.01)

Patent

CA 2646227

The invention relates to compounds of formula (I), wherein R1 to R11 have the meanings as described in the claims. Medicaments containing compounds of this type are useful in preventing or treating various diseases. The compounds can be used, amongst other things, for renal diseases such as acute or chronic kidney failure, for defects of the biliary function, for breathing disorders such as snoring or sleep apnea or for diseases of the central nervous system.

La présente invention concerne des composés de formule I dans laquelle R1 à R11 possèdent les significations figurant dans les revendications. Des médicaments qui contiennent des composés de ce type sont utiles pour prévenir ou traiter diverses maladies. Ainsi, il est possible d'utiliser ces composés, entre autres pour des maladies rénales telles que l'insuffisance rénale aiguë ou chronique, en cas de perturbations de la fonction biliaire, en cas de difficultés respiratoires telles que le ronflement ou l'apnée du sommeil ou dans des maladies du système nerveux central.

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