Process for substituted pyridines

Details Process for substituted pyridines Process for substituted pyridines

C - Chemistry, Metallurgy

07

D

C07D 213/75 (2006.01) A61K 31/44 (2006.01) C07B 43/04 (2006.01) C07D 213/30 (2006.01) C07D 213/73 (2006.01)

Patent

CA 2270386

This invention relates to processes for preparing compounds of formula (I) which are .beta.-adrenergic receptor agonists, and to processes for preparing certain intermediates of formula (II A) wherein R1 is nitro, amino or protected amino; R2 is H, fluoro, chloro CF3, nitro, (C1-C4)alkyl, (C1-C4)alkoxy, amino or protected amino; and X1 is OH or a suitable leaving group, used in that process. The invention also relates to novel compounds of the formulae (II).

Procédés de préparation de composés de formule (I) qui sont des agonistes du récepteur adrénergique B, et procédés de préparation de certains intermédiaires de formule (II<A>), dans lesquelles R<1> est nitro, amino ou amino protégé, R<2> est H, fluoro, chloro CF3, nitro, alkyle C1-C4, alcoxy C1-C4, amino ou amino protégé, et X<1> est OH ou un groupe labile approprié, utilisés dans lesdits procédés. La présente invention concerne également des composés des formules (II).

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