Solid dispersion product of n-aryl urea-based drugs

Details Solid dispersion product of n-aryl urea-based drugs Solid dispersion product of n-aryl urea-based drugs

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 31/337 (2006.01)

Patent

CA 2699301

A solid dispersion product comprising at least one N-aryl urea-based pharmaceutically active agent is obtained by a) preparing a liquid mixture containing the at least one active agent, at least one pharmaceutically acceptable matrix-forming agent, at least one pharmaceutically acceptable surfactant and at least one solvent, and b) removing the solvent(s) from the liquid mixture to obtain the solid dispersion product.

L'invention porte sur un produit de dispersion solide contenant au moins un agent N-aryle à base d'urée pharmaceutiquement actif, ledit produit étant obtenu par a) préparation d'un mélange liquide contenant le ou les agent(s) actif(s), au moins un agent matriciel pharmaceutiquement acceptable, au moins un agent de surface pharmaceutiquement acceptable et au moins un solvant; et b) retrait du/des solvant(s) dudit mélange liquide pour obtenir le produit de dispersion solide.

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