Process for the preparation of peptides

Details Process for the preparation of peptides Process for the preparation of peptides

C - Chemistry, Metallurgy

07

K

C07K 1/08 (2006.01) C07K 1/02 (2006.01) C07K 5/06 (2006.01) C07K 5/072 (2006.01)

Patent

CA 2394216

The present invention relates to a process for the preparation of peptides using an excess of an activated carboxylic component to acylate an amino component, wherein after the acylation an amine comprising a free anion or a latent anion is used as a scavenger of residual activated carboxylic functions. This process is useful for the preparation of oligo- and polypeptides and, more generally, in the preparation of compounds containing one or more amide bonds.

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