C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A61P 7/02 (2006.01) C40B 30/04 (2006.01) C40B 40/06 (2006.01)
Patent
CA 2717045
The present invention is based on the discovery of genetic polymorphisms that are associated with venous thrombosis. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
La présente invention porte sur la découverte de polymorphismes génétiques qui sont associés à une thrombose veineuse. En particulier, la présente invention porte sur des molécules d'acide nucléique contenant les polymorphismes, sur des protéines variantes codées par de telles molécules d'acide nucléique, sur des réactifs pour détecter les molécules d'acide nucléique polymorphes et de protéines, et sur des procédés d'utilisation de l'acide nucléique et des protéines ainsi que sur des procédés d'utilisation de réactifs pour leur détection.
Bare Lance
Bezemer Irene D.
Devlin James
Reitsma Pieter H.
Rosendaal Fritz R.
Celera Corporation
Fetherstonhaugh & Co.
Leiden University Medical Center (lumc) Acting On Behalf Of Acad
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