Novel tumor suppressor gene, dpc4

Details Novel tumor suppressor gene, dpc4 Novel tumor suppressor gene, dpc4

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 35/12 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 14/82 (2006.01) C07K 16/32 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2243301

Polynucleotide and polypeptide sequences encoding a novel tumor suppressor gene, DPC4, are provided. Also included is a method for detecting a cell proliferative disorder associated with DPC4. DPC4 is a marker which can be used diagnostically, prognostically and therapeutically over the course of disorders associated with DPC4.

L'invention se rapporte à des séquences de polynucléotides et de polypeptides codant un nouveau gène suppresseur de tumeur, le DPC4, ainsi qu'à un procédé de détection de troubles de la multiplication cellulaire associée au DPC4. Le DPC4 est un marqueur qui peut être utilisé dans les diagnostics, les pronostics et les thérapies effectués au cours de l'évolution de troubles associés au gène DPC4.

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