C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/437 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61K 31/517 (2006.01) A61K 31/5377 (2006.01) A61K 31/551 (2006.01) A61P 3/06 (2006.01) C07D 295/145 (2006.01) C07D 403/04 (2006.01) C07D 413/04 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2395249
The invention relates to substituted piperazine derivatives of general formula (I), wherein Ra, Rb, Rc, Rf, Rg, X, m and n have the meanings given in claim no.1, and isomers and salts thereof, especially physiologically suitable salts thereof, which are valuable inhibitors of microsomal triglyceride transfer protein (MTP). The invention also relates to medicaments containing these compounds and to the use and production of said compounds.
L'invention concerne des dérivés de pipérazine substitués de la formule générale (I), où R¿a?, R¿b?, R¿c?, R¿f?, R¿g?, X, m et n ont la signification donnée dans la revendication 1, leurs isomères et leurs sels, notamment leurs sels physiologiquement tolérables, qui sont de précieaux inhibiteurs de la protéine de transfert triglycéride microsomale (MTP). L'invention concerne également les médicaments contenant ces composés, leur utilisation et leur production.
Heckel Armin
Lehmann-Lintz Thorsten
Mark Michael
Thomas Leo
Boehringer Ingelheim Pharma Gmbh & Co. Kg
Boehringer Ingelheim Pharma Kg
Fetherstonhaugh & Co.
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