Cell stress regulated human mhc class i gene

Details Cell stress regulated human mhc class i gene Cell stress regulated human mhc class i gene

G - Physics

01

N

G01N 33/574 (2006.01) A01K 67/027 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/74 (2006.01) C07K 16/28 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2275141

The present invention provides various methods by which the use of certain MHC- related molecules can be exploited in understanding and regulating the immune response. More particularly, the present invention describes the use of molecules expressed by certain cell types as markers, reagents and targets in the diagnosis and treatment of certain disease states including GVHD, cancer and the like.

La présente invention concerne différentes méthodes selon lesquelles l'utilisation de certaines molécules apparentées au complexe majeur d'histocompatibilité est exploitée pour comprendre et réguler la réaction immunitaire. En particulier, l'invention concerne l'utilisation de molécules exprimées par certaines types de cellules, en tant que marqueurs, réactifs et cibles dans le diagnostic et le traitement de certaines maladies, par ex. la réaction du greffon contre l'hôte, le cancer ou similaire.

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