C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) C07H 21/00 (2006.01) C07K 14/21 (2006.01) C12N 15/11 (2006.01) C12P 21/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2378687
The present invention provides the genomic sequences of a library of purified nucleic acid molecules, or their complements, comprising the genome of Moraxella catarrhalis. The invention also provides the identification of open reading frames contained within the nucleic acid molecules of the library. The present invention further provides for the use of the nucleic acid molecules, their complements or fragments, and proteins or portions thereof for identifying ligands and useful diagnostic and therapeutic compositions. In addition the invention provides for vectors, host cells and methods for producing M-catarrhalis proteins or portions thereof.
L'invention concerne des séquences génomiques d'une librairie de molécules d'acides nucléiques purifiés, ou leurs compléments, qui renferment le génome de Branhamella catarrhalis. L'invention concerne en outre l'identification de cadres de lecture ouverts contenus dans les molécules considérées. L'invention concerne également l'utilisation de ces molécules, de leurs compléments ou fragments, et de protéines correspondantes ou de parties de ces protéines pour identifier des ligands et des compositions diagnostiques et thérapeutiques utiles. L'invention concerne enfin des vecteurs, des cellules hôtes et des procédés relatifs à l'élaboration de protéines de Branhamella catarrhalis ou de parties de ces protéines.
Berg Kim L.
Lagace Robert E.
Patterson Chandra
Elitra Pharmaceuticals Inc.
Fetherstonhaugh & Co.
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