Use of dextran covalently bound to charged groups for...

Details Use of dextran covalently bound to charged groups for... Use of dextran covalently bound to charged groups for...

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 51/06 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2347424

A compound for local, i.e. intratumoral or intracavitary administration, for targeting tumors comprising dextran, the charge of which has been modified through covalent binding of charged groups, such as charged amino acids. The compound further comprises a functional group for treating or imaging the tumor.

L'invention concerne un composé destiné à une administration locale, c'est-à-dire intratumorale ou intracavitaire, qui permet le ciblage de tumeurs. Ce composé comprend du dextrane, dont la charge a été modifiée au moyen d'une liaison covalente de groupes chargés, tels que des acides aminés chargés. Il comporte également un groupe fonctionnel destiné au traitement de la tumeur ou à sa représentation sous formes d'images.

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