Topical treatment of psoriasis using neutralizing antibodies...

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) C07K 16/24 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2291144

A method for treatment of psoriasis and other inflammatory skin conditions, comprising applying topically a composition containing as active ingredient an antibody neutralizing human Interleukin-8 (IL-8) biological activity together with a pharmaceutically acceptable carrier. The invention also includes a pharmaceutical composition for treating inflammatory skin conditions. The pharmaceutical composition includes antibodies that neutralize human Interleukin-8 (IL-8) biological activity.

L'invention concerne une méthode de traitement du psoriasis ou d'autres dermatoses inflammatoires, qui consiste à appliquer une composition topique contenant, comme principe actif, un anticorps apte à neutraliser l'activité biologique de l'interleukine 8 humaine (IL-8), ainsi qu'un transporteur pharmaceutiquement acceptable. L'invention concerne également une composition pharmaceutique pouvant traiter des dermatoses inflammatoires et contenant des anticorps aptes à neutraliser l'activité biologique de l'interleukine 8 humaine (IL-8).

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