Muscarinic antagonists

Details Muscarinic antagonists Muscarinic antagonists

C - Chemistry, Metallurgy

07

D

C07D 221/20 (2006.01) A61K 31/4523 (2006.01) A61P 25/00 (2006.01) C07D 211/96 (2006.01)

Patent

CA 2484217

The invention described herein are compounds in accordance with formula I:. I Iwherein R1, R2, R3, R4, R5, R6, R2, R8, R9, n, X, and Z are as defined herein, pharmaceutical compositions containing at least one compound of formula I, methods of preparation thereof, and methods of treating disorders with at least one compound of formula I or at least one compound of formula I in association with at least one acetylcholinesterase inhibitor.

L'invention concerne des composés de formule I, dans laquelle R¿1?, R¿2?, R¿3?, R¿4?, R¿5?, R¿6?, R¿2?, R¿8?, R¿9?, n, X et Z sont tels que définis dans le descriptif, des compositions pharmaceutiques contenant un composé de formule I, leurs procédés de préparation ainsi que les méthodes de traitement des troubles à l'aide d'au moins un composé de formule I ou d'au moins un composé I combiné avec au moins un inhibiteur d'acétylcholinestérase.

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