Method for treatment of skin lesions associated with...

A - Human Necessities – 61 – K

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A61K 38/16 (2006.01)

Patent

CA 2190564

The invention is a method for treatment of cutaneous cell-proliferativedisorders. More specifically, the method of the invention is useful in mitigating and inducing remission of lesions associated with such disorders and in controlling related symptoms of the disorders (such as scaling and itching). According to the method of the invention, an invertebrate neurotoxin is administered to the skin of the host at or near the site of a lesion. The preferred neurotoxin for use in the method of the invention is Botulinum toxin, particularly Botulinum toxin A.

L'invention porte sur une méthode de traitement des affections cutanées caractérisées par une prolifération cellulaire. Plus spécifiquement, la méthode de l'invention est utile pour atténuer les lésions liées à ces affections et provoquer leur rémission et pour limiter les symptômes liés à ces affections (comme la desquamation et les démangeaisons). Selon la méthode de l'invention, une neurotoxine d'invertébré est appliquée sur la lésion cutanée de l'hôte ou à proximité. La neurotoxine privilégiée pour utilisation dans le cadre de la méthode de l'invention est la toxine botulinique, et particulièrement la toxine botulinique de type A.

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