A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/12 (2006.01) A61K 39/29 (2006.01)
Patent
CA 2453260
The invention relates to a vaccine antigen formulation containing the following main components: a) one or more DNAs that express one or more proteins in the immunised individual and b) a viral antigen, in suitable proportions. The novelty of the invention lies in the potentiating effect exerted by at least one of the components on the immune response generated against the other. The invention also relates to the development of novel formulations that minimise the number of components that can amplify and potentiate the range of immune response against different pathogenic entities and generate combined vaccines against pathogenic entities. Said formulations are suitable for use in the pharmaceutical industry for prophylactic and/or therapeutic purposes in individuals.
L'invention concerne une formulation d'antigènes vaccinaux, contenant comme composants principaux: a-) un ou plusieurs ADN exprimant une ou plusieurs protéines chez l'individu immunisé et b-) un antigène viral, dans des proportions adéquates. La nouveauté de l'invention réside dans l'effet potentialisateur exercé par au moins un des composants sur la réponse immune générée contre l'autre. L'invention concerne également la mise au point de nouvelles formulations minimisant le nombre de composants pouvant étendre et potentialiser le spectre de réponse immune contre différentes entités pathogènes, et générer des vaccins combinés contre des entités pathogènes. Ces formulations peuvent être utilisées dans l'industrie pharmaceutique à des fins prophylactiques et/ou thérapeutiques.
Acosta Rivero Nelson
Alvarez Obregon Julio C.
Alvarez-Lajonchere Ponce de Leon Liz
Duenas Carrera Santiago
Martinez Donato Gillian
Centro de Ingenieria Genetica Y. Biotecnologia
Deeth Williams Wall Llp
LandOfFree
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