Contrast agents comprising metal particles encapsulated in...

Details Contrast agents comprising metal particles encapsulated in... Contrast agents comprising metal particles encapsulated in...

A - Human Necessities

61

K

A61K 49/22 (2006.01) A61K 41/00 (2006.01) A61K 49/18 (2006.01)

Patent

CA 2451852

The present invention relates to a composition that includes gadolinium particles encapsulated in microsphere shells. The composition is suitable for use as a contrast agent with am plurality of imaging modalities, including, for example, ultrasound, magnetic resonance imaging, and computed temography. The compositions also also are useful for therapeutic applications, including neutron capture therapy.

La présente invention a trait à une composition comprenant des particules de gadolinium encapsulées dans des enveloppes microsphériques. Ladite composition est adaptée à une utilisation en tant que substance de contraste, avec une pluralité de modalités d'imagerie, comme par exemple l'imagerie par ultrasons, l'imagerie par résonance magnétique et la tomographie par ordinateur. Ces compositions servent également pour des applications thérapeutiques, notamment pour la thérapie par capture de neutrons.

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