Method for improving the oral administration of alpha-lipoic...

Details Method for improving the oral administration of alpha-lipoic... Method for improving the oral administration of alpha-lipoic...

A - Human Necessities

61

K

A61K 47/18 (2006.01) A61K 31/385 (2006.01) A61P 3/02 (2006.01)

Patent

CA 2641675

The invention provides a method for reducing esophageal irritation associated with alpha-lipoic acid upon oral administration through the use of the trometamol salt of alpha-lipoic acid. The present invention also provides for the increased solubility of alpha-lipoic acid through the use of the trometamol salt of alpha-lipoic acid. The trometamol salt of alpha-lipoic acid, as provided by the present invention can be used as a substitute for regular, non-salt forms alpha-lipoic acid in dietary supplement compositions.

L'invention concerne un procédé de réduction de l'irritation AEsophagienne associée à l'acide alpha-lipoïque administré par voie orale en utilisant le sel de trométamol de l'acide alpha-lipoïque. La présente invention concerne également la solubilité accrue de l'acide alpha-lipoïque grâce à l'utilisation du sel de trométamol de l'acide alpha-lipoïque. Le sel de trométamol de l'acide alpha-lipoïque selon la présente invention peut être utilisé comme substitut pour les formes normales, autres que des sels, de l'acide alpha-lipoïque dans des compositions de compléments diététiques.

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