Benzothiazole derivatives

Details Benzothiazole derivatives Benzothiazole derivatives

C - Chemistry, Metallurgy

07

D

C07D 417/14 (2006.01) A61K 31/422 (2006.01) A61K 31/423 (2006.01) A61K 31/427 (2006.01) A61K 31/428 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) A61K 31/455 (2006.01) A61K 31/496 (2006.01) A61K 31/5375 (2006.01) A61K 31/5377 (2006.01) A61K 31/541 (2006.01) A61K 31/5513 (2006.01) C07D 277/82 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2413086

The present invention relates to compounds of the general formula (I) and to their pharmaceutically acceptable salts for the treatment of diseases related to the adenosine A2 receptor, novel compounds of formula I-A per se,their manufacture, medicaments based on a compound in accordance with the invention and their production as well as the use of compounds of compounds of formula I in the control or prevention of illnesses based on the modulation of the adenosine system, such as Alzheimer's disease, Parkinson's disease, neuroprotection, schizophrenia, anxiety, pain, respiration deficits, depression, asthma, allergic responses hypoxia, ischaemia, seizure and substance abuse. Furthermore, compounds of the present invention may be useful as sedatives, muscle relaxants, antipsychotics, antiepileptics, anticonvulsants and cardiaprotective agents.

Cette invention se rapporte à des composés représentés par la formule générale (I) et à leurs sels acceptables sur le plan pharmaceutique, utilisés dans le traitement des maladies associées au récepteur d'adénosine.

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