Agents for controlling biological fluids and methods of use...

A - Human Necessities – 61 – L

Patent

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A61L 15/42 (2006.01) A61L 26/00 (2006.01)

Patent

CA 2595132

Therapeutic formulations adapted for positive-pressure application for controlling biological fluid at a desired site in a subject, absorbent articles comprising therapeutic formulations, and anti-infective devices coated with therapeutic formulations, said formulations comprising about 25 % to about 99 % by weight liquid-crystal forming compound and 0 % to about 75 % by weight solvent. In addition, methods of using said formulations including methods for controlling biological fluid at a desired site in a subject, methods for controlling blood loss, and methods for facilitating effective closure of a vascular wound or incision site at a desired site in a subject are disclosed, the methods comprising administering particular formulations comprising liquid-crystal forming compounds and solvents that are described herein.

L'invention concerne des formulations thérapeutiques conçues pour une application de pression positive afin de contrôler un fluide biologique sur un site voulu chez un sujet, des articles absorbants comprenant des formulations thérapeutiques et des dispositifs anti-infectieux revêtus des formulations thérapeutiques, lesquelles contiennent d'environ 25 % à environ 99 % en poids d'un composé formant des cristaux liquides et 0 % à environ 75 % en poids de solvant. L'invention concerne également des méthodes utilisant ces formulations, notamment des méthodes permettant de contrôler un fluide biologique sur un site voulu chez un sujet, des méthodes de contrôler une perte sanguine et des méthodes facilitant la fermeture efficace d'une lésion vasculaire ou d'un site d'incision sur un site voulu chez un sujet, ces méthodes consistant à administrer des formulations particulières comprenant des composés formant des cristaux liquides et des solvants.

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