C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/210, 260/240
C07D 243/14 (2006.01) A61K 31/55 (2006.01) C07D 243/24 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 471/04 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2032427
39/RDM20 18028 TITLE OF THE INVENTION NEW BENZODIAZEPINE ANALOGS ABSTRACT OF THE DISCLOSURE Benzodiazepine analogs of the formula: Image I are disclosed which are antagonists of gastrin and cholecystokinin (CCK) with enhanced aqueous solubility and have properties useful in the treatment of disorders of gastric secretion, appetite regulation, gastrointestinal motility, pancreatic secretion, and dopaminergic function, as well as in treatment producing potentiation of morphine and other opiate analgesics.
Bock Mark G.
Evans Ben E.
Freidinger Roger M.
Bock Mark G.
Evans Ben E.
Freidinger Roger M.
Merck & Co. Inc.
Swabey Ogilvy Renault
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