Gene expression profiling for identification, monitoring,...

Details Gene expression profiling for identification, monitoring,... Gene expression profiling for identification, monitoring,...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2682916

A method is provided in various embodiments for determining a profile data set for a subject with cervical cancer or conditions related to cervical cancer based on a sample from the subject, wherein the sample provides a source of RNAs. The method includes using amplification for measuring the amount of RNA corresponding to at least 1 constituent from Tables 1-5. The profile data set comprises the measure of each constituent, and amplification is performed under measurement conditions that are substantially repeatable.

Dans divers modes de réalisation, l'invention concerne une méthode permettant de déterminer un ensemble de données de profil chez un sujet atteint d'un cancer du col de l'utérus ou pour des états en rapport avec un tel cancer à partir d'un échantillon pris sur le sujet, échantillon qui constitue une source d'ARN. Cette méthode consiste à procéder à une amplification pour mesurer la quantité d'ARN correspondant à au moins 1 constituant pris dans les tableaux 1-5. L'ensemble des données de profil comprend la mesure de chaque constituant et l'amplification se déroule dans des conditions de mesure sensiblement reproductibles.

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