C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/85 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 405/12 (2006.01)
Patent
CA 2576973
The invention concerns benzamide compounds of Formula (I), wherein R1a, R1b, R1c, R2, R3, R4, m and n have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours or other proliferative conditions which are sensitive to the inhibition of histone deacetylase (HDAC).
L'invention concerne des composés de benzamide de formule (I). Dans cette formule, R1a, R1b, R1c, R2, R3, R4, m et n correspondent aux significations définies dans la description. L'invention concerne des procédés pour la préparation de ces composés, des compositions pharmaceutiques les contenant et leur utilisation dans la fabrication d'un médicament servant d'agent antiprolifératif pour traiter ou pour prévenir des tumeurs ou d'autres troubles prolifératifs sensibles à l'inhibition de l'histone désacétylase (HDAC).
Andrews David Michael
Gibson Keith Hopkinson
Graham Mark Andrew
Matusiak Zbigniew Stanley
Stokes Elaine Sophie Elizabeth
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