Process of manufacturing viral vaccines in suspension avian...

C - Chemistry – Metallurgy – 12 – N

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C12N 7/00 (2006.01) A61K 39/12 (2006.01) A61P 31/12 (2006.01) A61P 31/16 (2006.01) C12Q 1/70 (2006.01) C12N 5/0735 (2010.01)

Patent

CA 2604330

The present invention relates to the development and manufacturing of viral vaccines. In particular, the invention relates to the field of industrial production of viral vectors and vaccines, more in particular to the use of avian embryonic stem cells, preferably the EBx cell line derived from chicken embryonic stem cells, for the production of viral vectors and viruses. The invention is particularly useful for the industrial production of viral vaccines to prevent viral infection of humans and animals.

L'invention concerne le développement et la fabrication de vaccins viraux. Plus précisément, l'invention concerne le domaine de la production industrielle de vecteurs et de vaccins viraux, plus précisément encore, l'utilisation de cellules souches embryonnaires aviaires, de préférence, la lignée de cellules Ebx dérivées de cellules souches embryonnaires de poulets, aux fins de production de vecteurs et de vaccins viraux. Le développement et la fabrication de vaccins viraux selon l'invention sont spécialement utiles dans la production industrielle de vaccins viraux permettant de prévenir une infection virale chez les êtres humaines et les animaux.

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