Charged filtration membranes and uses therefor

Details Charged filtration membranes and uses therefor Charged filtration membranes and uses therefor

B - Operations, Transporting

01

D

B01D 67/00 (2006.01) B01D 61/14 (2006.01) B01D 69/02 (2006.01) B01D 69/12 (2006.01) B01D 71/10 (2006.01) B01D 71/22 (2006.01) C07K 1/34 (2006.01)

Patent

CA 2379413

The invention relates to charged filtration membranes and their use for separation of a protein from solvent, low molecular weight solutes or a mixture of proteins. Modification of the membranes to generate charge includes modification of membrane pores to alter charge within a pore and alter the size of a pore. Consequently, the protein is separated from other solutes in a mixture based on size as well as net protein charge and membrane charge.

La présente invention concerne des membranes de filtration chargées ainsi que leur utilisation pour séparer une protéine d'un solvant, de solutés présentant un poids moléculaire faible ou d'un mélange de protéines. La modification des membranes servant à produire une charge consiste en la modification des pores des membranes de manière à altérer, d'une part, la charge à l'intérieur d'un pore et, d'autre part, la taille d'un pore. Par conséquent, la protéine est séparée des autres solutés dans un mélange en fonction de la taille et des charges nettes de la protéine et de la membrane.

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