Method and system for magnetic resonance imaging, and use...

G - Physics – 01 – R

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Details

G01R 33/563 (2006.01) A61B 5/055 (2006.01) G01N 24/08 (2006.01) G01R 33/46 (2006.01)

Patent

CA 2761017

The present invention refers to a method for magnetic resonance imaging or nuclear magnetic resonance spectroscopy comprising emitting a radio frequency and gradient pulse sequence towards an object being subjected to a magnetic field, wherein said object comprises a molecule having an atom with a nuclear spin differing from 0, encoding, detecting and acquiring a magnetic resonance signal from said object corresponding to said emitted radio frequency and gradient pulse sequence, wherein the radio frequency and gradient pulse sequence comprises a first weighting block, a mixing block with duration t m and a second weighting block, and wherein encoding, detecting and acquiring the magnetic resonance signal from said object is limited to initial decay of the signal intensity / with increasing strength of at least one of the first weighting block and the second weighting block, wherein the variation of the initial signal decay rate with t m is analysed to obtain the apparent exchange rate AXR.

La présente invention concerne un procédé pour une imagerie par résonance magnétique ou une spectroscopie par résonance magnétique nucléaire. Le procédé consiste à émettre une suite d'impulsions de gradient et radiofréquence vers un objet qui est soumis à un champ magnétique, ledit objet comprenant une molécule comportant un atome dont le spin nucléaire diffère de 0 ; à coder, détecter et acquérir un signal de résonance magnétique à partir dudit objet correspondant à ladite suite d'impulsions de gradient et radiofréquence émise, ladite suite comprenant un premier bloc de pondération, un bloc de mélange d'une durée tm et un second bloc de pondération ; et le codage, la détection et l'acquisition du signal de résonance magnétique à partir dudit objet étant limités à la décroissance initiale de l'intensité du signal/avec l'augmentation de la puissance du premier bloc de pondération et/ou du second bloc de pondération. La variation du taux de décroissance du signal initial avec tm est analysée pour obtenir le taux d'échange apparent AXR.

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