A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/30 (2006.01)
Patent
CA 2099257
2099257 9211865 PCTABS00014 The invention discloses the use of human IGF-I or effective analogues thereof for the manufacture of a medicament for prevention or treatment of cardiac disorders. More specifically the medicament is used for the promotion of cardiac muscle protein synthesis, for prevention or treatment of cardiomyopathies, acute heart failure or acute insult including myocarditis or myocardial infarction and for improving of cardiac output by increasing heart stroke volume e.g. for treatment of myocardial infarction. The invention also discloses a composition comprising human IGF-I or effective analogues thereof together with additional proteins or peptides such as other growth factors, hormones, binding proteins or receptors for enhancing or improving the desired effect(s) of IGF-1 or its effective analogues and possibly pharmaceutically acceptable carrier or diluent for the prevention or treatment of cardiac disorders.
Gluckman Peter
Skottner Anna
Pharmacia Aktiebolag
Smart & Biggar
LandOfFree
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