Microemulsion preconcentrate comprising a renin inhibitor

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 31/00 (2006.01) A61K 9/107 (2006.01) A61K 31/165 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) A61P 25/00 (2006.01) A61P 27/06 (2006.01)

Patent

CA 2547195

The present invention relates to pharmaceutical compositions for oral administration comprising a .alpha.-amino-.gamma.-hydroxy-.omega.-aryl- alkanoic acid amide renin inhibitors as the active ingredient. In particular, the present invention relates to galenic formulations in the form of microemulsion preconcentrates comprising the active ingredient and at least one absorption enhancing excipient which preconcentrates provide spontaneously dispersible water-in-oil microemulsions which upon further dilution in aqueous medium, e.g., gastric fluids, convert to oil-in-water microemulsions. The present invention also relates to the processes for their preparation and to their use as medicaments.

La présente invention concerne des compositions pharmaceutiques administrées par voie orale comprenant des inhibiteurs de rénine amidique d'acide .delta.-amino-.gamma.-hydroxy-.omega.-aryl-alcanoïque comme ingrédient actif. Plus particulièrement, la présente invention concerne des préparations galéniques sous la forme de préconcentrés en microémulsion renfermant cet ingrédient actif et au moins un excipient renforçateur d'absorption, ces préconcentrés permettant d'obtenir des microémulsions eau dans huile spontanément dispersibles qui, lors d'une dilution supplémentaire dans un milieu aqueux, tel que les liquides gastriques, se transforment en microémulsions huile dans eau. La présente invention concerne également leurs procédés de préparation et leur utilisation comme médicaments.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Microemulsion preconcentrate comprising a renin inhibitor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Microemulsion preconcentrate comprising a renin inhibitor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Microemulsion preconcentrate comprising a renin inhibitor will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1745419

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.