A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/195 (2006.01) A61K 31/19 (2006.01) C07C 271/22 (2006.01) C07C 323/58 (2006.01) C07D 213/80 (2006.01) C07D 267/06 (2006.01) C07D 307/58 (2006.01) C07D 317/32 (2006.01) C07D 317/40 (2006.01)
Patent
CA 2449673
The present invention provides an extended release oral dosage form of prodrugs of gabapentin and other GABA analogs, which dosage forms exhibit reduced toxicity. The dosage forms are particularly useful in administering those prodrugs of gabapentin and other GABA analogs that are metabolized to form an aldehyle. The dosage forms of the invention are useful for treating or preventing diseases and/or disorders for which the parent gabapentin or other GABA analog are known to be therapeutically effective.
La présente invention concerne une forme de dosage à libération lente de promédicaments à faible toxicité à base de gabapentine et d'autres analogues du GABA, administrée par voie orale. Ces formes de dosage sont particulièrement utiles pour l'administration de ces promédicaments à base de gabapentine et d'autres analogues du GABA métabolisés pour former un aldéhyde. Les formes de dosage de la présente invention sont destinées au traitement ou à la prévention de maladies et/ou de troubles sur lesquels la gabapentine ou les analogues du GABA ont un effet thérapeutique.
Cundy Kenneth C.
Gallop Mark A.
Fetherstonhaugh & Co.
Xenoport Inc.
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