A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/55 (2006.01) A61K 9/48 (2006.01) A61K 31/69 (2006.01) A61K 47/06 (2006.01) A61K 47/14 (2006.01) A61K 47/26 (2006.01) A61K 47/34 (2006.01) A61K 47/44 (2006.01)
Patent
CA 2310775
A composition for the delivery across a mucosal surface of a lipophilic thrombin inhibitor comprising a lipophilic thrombin inhibitor and a non-ionic surfactant. Preferably, the mucosal surface is in the gastrointestinal tract, nose, mouth, rectum or vagina. Advantageously, the thrombin inhibitor is a peptide boronic acid or ester derivative thereof. Conveniently, the non-ionic surfactant is an ethoxylated glyceride. Suitably, the composition is contained within a capsule. In addition, the invention also relates to methods of making said compositions and the use of said compositions in medicine.
L'invention concerne une composition prévue pour être administrée par les muqueuses d'un inhibiteur de thrombine lipophile, comprenant un inhibiteur de thrombine lipophile, et un tensioactif non ionique. De préférence, les muqueuses sont celles tapissant l'appareil gastro-intestinal, le nez, la bouche, le rectum ou le vagin. De manière avantageuse, l'inhibiteur de thrombine est un acide borique de peptides ou un dérivé d'ester de ce dernier. De manière pratique, le tensioactif non ionique est un glycéride éthoxylé. De manière appropriée, la composition est contenue dans une gélule. En outre, l'invention concerne des procédés de fabrication desdites compositions et l'utilisation de ces compositions en médecine.
Russell Reyneke
West Pharmaceutical Services Drug Delivery & Clinical Research C
LandOfFree
Mucosal delivery system comprising lipophilic thrombin... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Mucosal delivery system comprising lipophilic thrombin..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mucosal delivery system comprising lipophilic thrombin... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1745823