4-aryl-3-(heteroarylureido)quinoline derivatives

Details 4-aryl-3-(heteroarylureido)quinoline derivatives 4-aryl-3-(heteroarylureido)quinoline derivatives

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/47 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) C07D 215/36 (2006.01) C07D 215/38 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2108014

2108014 9219614 PCTABS00017 Compounds of formula (I) and the pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, m, X and Q are as defined below, and novel intermediates used in the synthesis of such compounds. The compounds of formula (I) are inhibitors of acyl coenzyme A: cholesterol acyltransferase (ACAT) and are useful as hypolipidemic and antiatherosclerosis agents.

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