Methods and compositions for inhibiting adhesion by...

A - Human Necessities – 61 – K

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A61K 38/44 (2006.01) A61K 8/66 (2006.01) A61K 38/50 (2006.01) A61P 31/00 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 2395610

The present invention is directed generally to compositions and methods for enzymatic reduction of adhesion by a microorganism to cells, tissues, extracellular matrix, teeth, and/or dental prostheses. The compositions of the invention include pharmaceutical compositions and oral care compositions containing an enzyme that can reduce binding of a microbe to a cell, a tissue, or a surface. Suitable enzymes include a polyphenol oxidase and an asparaginase.

Cette invention se rapporte de manière générale à des compositions et à des procédés permettant une réduction enzymatique de l'adhérence des micro-organismes sur les cellules, les tissus, les matrices extracellulaires, les dents et/ou les prothèses dentaires. Cette invention concerne des compositions pharmaceutiques et des compositions de soins buccaux contenant une enzyme qui permet de réduire le pouvoir de fixation d'un microbe sur une cellule, un tissu ou une surface. Les enzymes convenant pour ces compositions comprennent une polyphénol oxydase et une asparaginase.

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