A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/20 (2006.01) A61K 31/19 (2006.01)
Patent
CA 2589655
A method and composition for blood lipid therapy that comprises administering to the subject an effective amount of a PPAR agonist and/or antagonist and an omega-3 fatty acid. The methods and compositions include combination products or concomitant therapy for the treatment of subjects with hypertriglyceridemia, hypercholesteremia, mixed dyslipidemia, vascular disease, a rtheroscl erotic disease and related conditions, obesity, the prevention or reduction of cardiovascular and vascular events, the reduction of insulin resistance, fasting glucose levels and postprandial glucose levels, and/or the reduction of incidence and/or the delay of onset of diabetes.
L'invention concerne un procédé et une composition destinés au traitement des lipides du sang et consistant à administrer à un sujet une quantité efficace d'un agoniste et/ou antagoniste PPAR et d'un acide gras oméga-3. Les procédés et compositions comprennent des produits composites ou un traitement concomitant destinés au traitement de patients souffrant de : hypertriglycéridémie, hypercholestérolémie, dyslipidémie mixte, maladie vasculaire, maladie athérosclérotique et des états associés, obésité ; et à la prévention ou la diminution d'événements cardio-vasculaires et vasculaires, la diminution de la résistance à l'insuline, des taux de glucose à jeun et des taux de glucose postprandiaux et/ou à la réduction de l'incidence et/ou le retard de l'apparition de diabètes.
Bobotas George
Rongen Roelof M. L.
Shalwitz Robert A. Ms
Reliant Pharmaceuticals Inc.
Smart & Biggar
LandOfFree
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