Method of treating prostatic diseases using active vitamin d...

Details Method of treating prostatic diseases using active vitamin d... Method of treating prostatic diseases using active vitamin d...

A - Human Necessities

61

K

A61K 31/59 (2006.01) A61K 31/58 (2006.01) A61K 31/592 (2006.01) A61K 45/00 (2006.01) A61P 13/08 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2276606

The invention provides therapeutic methods for inhibiting, ameliorating or alleviating the hyperproliferative cellular activity of diseases of the prostate, e.g., prostatic cancer and prostatic hyperplasia, which includes administering to a patient in need thereof an active vitamin D analogue. Cell differentiation is promoted, induced or enhanced without causing to the patient dose-limiting hypercalcemia and hypercalciuria.

L'invention concerne des procédés thérapeutiques pouvant inhiber, améliorer ou atténuer l'activité cellulaire hyperproliférative de maladies de la prostate (cancer prostatique ou hyperplasie prostatique, par exemple). Les procédés consistent à administrer à un patient sous traitement un analogue actif de la vitamine D. Une différenciation cellulaire est ainsi promue, induite ou renforcée sans provoquer chez le patient l'hypercalcémie ou l'hypercalciurie limitant la posologie.

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