Substituted triazoles as angiotensin ii inhibitors

Details Substituted triazoles as angiotensin ii inhibitors Substituted triazoles as angiotensin ii inhibitors

C - Chemistry, Metallurgy

07

D

C07D 249/12 (2006.01) A61K 31/41 (2006.01) C07D 403/10 (2006.01)

Patent

CA 2088347

ABSTRACT Substituted Triazoles as Angiotensin II Inhibitors This invention relates to novel bis-biphenyl substituted 3-mercapto-1,2,4- tetrazoles and to pharmaceutically acceptable salts thereof. The compounds are angiotensin II receptor antagonists, and are useful in treating hypertension (lowering high blood pressure), congestive heart failure, elevated ocular pressure, cerebral stroke, angina, cardiac insufficiency, myocardial infarction or diabetic nephropathy. The invention also relates to a pharmaceutical composition comprising a compound of the invention, a method of treating a physiological condition in a mammal that is mediated by angiotensin II which comprises administering to the mammal an effective amount of a compound of the invention, and novel processes for preparing the compounds of the invention.

Affiliated with

Also associated with

Rating

Substituted triazoles as angiotensin ii inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted triazoles as angiotensin ii inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted triazoles as angiotensin ii inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1748512