Meg-1 protein

Details Meg-1 protein Meg-1 protein

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2376404

DNA highly frequently expressed in mesangial cells, and a protein (meg-1) encoded by this DNA. These substances are useful in identifying mesangial cells, detecting abnormalities in mesangial cells, etc. Moreover, the function of mesangial cells is clarified based on the function of the above protein. It is therefore expected that the causes of diseases concerning mesangial cell will be discovered thereby. These substances are also expected as being applicable to the treatment, diagnosis, etc. of diseases concerning mesangial cells.

L'invention concerne de l'ADN à expression très fréquente dans les cellules mésangiales, et une protéine (Meg-1) codée par cet ADN. Les substances considérées sont très utiles pour l'identification des cellules mésangiales, la détection des anomalies dans lesdites cellules, etc. Par ailleurs, la fonction des cellules mésangiales est clarifiée sur la base de la fonction de la protéine considérée. On s'attend donc à ce que cela permette de découvrir les causes des maladies relatives aux cellules mésangiales. On s'attend en outre à ce que les substances considérées soient applicables en liaison avec le traitement, le diagnostic, etc. des maladies relatives aux cellules mésangiales.

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